Detailed Selling Lead Description
Brand: YC
Model: cheryl@chembj.com
Price: USD 1 / gram
Min. Order: 5g gram
Cardiovascular Diseases Treatment
Acadesine CAS: 2627-69-2
Alias: AICAR; AICA-RIBOSIDE; AMPK; Z-RIBOSIDE
EINECS: 220-097-5
Molecular Formula: C9H14N4O5
Molecular Weight: 258.23
Storage Temp.: 20°c
Solubility H2O: >10 Mg/Ml
Melting Point: 214-215 ° C
Boiling Point: 726.3 ° C at 760 mmHg
Assay: 98%
Apperance: White or off-white powder.
Product Categories: Bases & Related Reagents;Carbohydrates & Derivatives;Nucleotides;Protein Kinase;ARASINE;Cardiovascular APIs;PI3K/Akt/mTOR
Usage: Pharmaceutical intermediates. For the treatment of cardiovascular diseases
Functions:AICAR (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.
----------Additional Information ------------
Place of origin : China
Brand : YC
Certificate : ISO9001, KOSHER, GMP, SGS
Minimum order quantity : 5 Grams
Production capacity : 1000 Kilograms/Month
-----------Delivery Information -------------
Packing : Foil bag/tin or as your request
Payment : T/T, Western Union, MoneyGram
Port : Shanghai, Shenzhen, Hongkong
Shipment method : EMS, DHL, FeDex, UPS, etc
Leading time : Within 24 hours after payment
Delivery time : safe & timely, around 4 days after payment.
----------Our Competitive Advantages -----------
1,Rich experience.
Our company is a professional production leading factory in China in pharmaceutical area of many years
2,Great quality, purity and favourable.
Our company is a professional leading factory in China in pharmaceutical area.Good quality is one of our secret success.
3,Safe and fast delivery.
We have stock, so we can delivery quickly at the very day when receive the payment.
4,Package: Professional packing with professional materials
5,Competitive Prices : Low price with high qulity
6,Good after-sales service : making all efforts to meet customers' need.