Brand: YC
Model: Skype: tom131393
Price: USD 1 / g
Min. Order: 10 g g
Regorafenib CAS:755037-03-7

Product Name: Regorafenib
CAS: 755037-03-7
MF: C21H15ClF4N4O3
MW: 482.8154128
Product Categories: Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Anti-cancer&immunity

Usage:
1.It inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent.
2.BAY 73-4506 (Regorafenib) is a multikinase inhibitor with IC50 of 17, 40 and 69 nM c-KIT, VEGFR2, B-Raf.
3.Regorafenib (BAY 73-4506) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively

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