Brand: YC
Model: Skype: tom131393
Price: USD 1 / g
Min. Order: 10 g g
Esomeprazole sodium CAS: 161796-78-7

Product Name: Esomeprazole sodium
CAS: 161796-78-7
MF: C34H36MgN6O6S2
MW: 713.12
Product Categories: ACTIVE PHARMACEUTICAL INGREDIENTS
Appearance : Beige Solid
Usage : (S)-Omeprazole is the (S)-enantiomer of Omeprazole (O635000) a gastric proton-pump inhibitor. (S)-Omeprazole is more potent that its (R)-enantiomer and is used in the treatment of gastroesophageal ref lux disease as well as gastrointestinal ulcers associated with Crohn's disease.

Application :
Esomeprazole sodium (Nexium) is a sodium salt of esomeprazole that is a potent proton pump inhibitor with an IC50 of 0.076 mg/kg. Esomeprazole sodium (Nexium) suppresses gastric acid secretion by specific inhibition of the H+/K+-ATPase in the gastric parietal cell. Esomeprazole sodium (Nexium) is used in the treatment of dyspepsia, peptic ulcer disease, gastroesophageal reflux disease and Zollinger-Ellison syndrome. Esomeprazole is the S-enantiomer of omeprazole. The S- and R-isomers of omeprazole are protonated and converted in the acidic compartment of the parietal cell forming the active inhibitor, the achiral sulphenamide. By acting specifically on the proton pump, esomeprazole blocks the final step in acid production, thus reducing gastric acidity. This effect is dose-related up to a daily dose of 20 to 40 mg and leads to inhibition of gastric acid secretion.

Related products :
Ticagrelor CAS: 274693-27-5
Saracatinib (AZD0530) CAS: 379231-04-6
Lansoprazole CAS: 103577-45-3
Flutamide CAS: 13311-84-7
Cyclophosphamide Monohydrate CAS: 6055-19-2
Binimetinib (MEK162, ARRY-162, ARRY-438162) CAS: 606143-89-9