Detailed Selling Lead Description
Brand: zzyc
Model: 1400-61-9
Min. Order: 10g
Alias: nystatin; mikeding; nystatin; mikeding, nystatin; nystatin dihydrate; nystatin (mycinomycin)
Molecular formula:C47H75NO17
Molecular weight: 926.09
CAS number: 1400-61-9
Content: 99%
Traits: yellow or brown-yellow powder; similar to grain odor, moisture-priming. Soluble in dimethylformamide, slightly soluble in methanol, very slightly soluble in water, insoluble in acetone, chloroform or ether.
Stability: Unstable to light, air, acid and alkali. Aqueous solution is very unstable. It can lose 50% when stored at 37 degrees Celsius for 1 week.
Pharmacological effects: This product is a polyene antifungal drug, has a broad-spectrum anti-fungal effect, is a membrane permeability enhancer, the most sensitive to Candida. Aspergillus, hair trichophyton, stably cocci, epidermophyton and microsporum are sensitive to this product. The minimum inhibitory concentration (MIC) is usually 1.56-6.25 μg/ml. This product also has antibacterial activity against coccidioides and histoplasmosis. It also has an inhibitory effect on trichomoniasis. The mechanism of action is the combination of specific sterols on the fungal cell membrane, resulting in destruction of the plasma membrane and permeability changes so that important cell contents leak out and die, killing the fungus.
Uses: Mainly used for internal treatment of gastrointestinal fungal infections or external surface fungal infections. For example, fungal gastritis of cattle, chicken and turkey cystic fungal disease, and mastitis caused by Aspergillus and Mucor are also effective. Inhalation of the pneumonia caused by Aspergillus fumigatus is also effective. This product is also used for long-term use of broad-spectrum antibiotics caused by fungal double infection.