2 - pyridinecarboxylic acid
Product Category: Pharmaceutical raw materials and intermediates
Product content: ≥ 99%
Chemical Formula: C6H5NO2
CAS Number: 98-98-6
2 - pyridinecarboxylic acid
Quality Standard: CP
Packing: 25,50 kg / barrel
Product Description: white powder
Properties: white needle crystal. Melting point 134-136 ℃, Yu Bing acid soluble, almost insoluble in ether, chloroform and carbon disulfide.
Preparation Methods: 50g2-picoline 2500ml adding water, heat stirring, adding 90g of potassium permanganate, about 1h before adding 90g of potassium permanganate second. Additional 500ml of water and continue heating 2-2.5h, until the purple disappears. Cooling, filter out the manganese dioxide precipitate, washing with hot water. Decompression will be concentrated filtrate, filtration. Concentrate acidification with concentrated hydrochloric acid to Congo red and dry after the evaporation of its 250ml95% ethanol and boiled returning seized 1h. Filtration, filter cake with 95% ethanol extraction, the combined filtrate and the ethanol extract, access to dry hydrogen chloride, to the crystal until the beginning of precipitation. Cooling to 10 ℃, and then to run and pass hydrogen chloride,
Filter out picolinate hydrochloride, after drying a 43-44g (hydrochloride salt, melting point 210-212 ℃).